Liangqin Guo : rechercher sur Z-Library

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1

Geniposide attenuates inflammatory response by suppressing P2Y14 receptor and downstream ERK1/2 signaling pathway in oxygen and glucose deprivation-induced brain microvascular endothelial cells

Li, Fanghe, Li, Weihong, Li, Xingguang, Li, Feng, Zhang, Linpeng, Wang, Bingce, Huang, Guangrui, Guo, Xiaojin, Wan, Liangqin, Liu, Yongqiang, Zhang, Sai, Kang, Soyeon, Ma, Jiabao

Journal:

Journal of Ethnopharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 4.47 MB

english, 2016

2

ChemInform Abstract: Preparation of 3,4-Fused-spiro[furan-5(5H),4′-piperidin]-2-one.

Jian Liu, Tianying Jian, Liangqin Guo, Tzvetomira Atanasova, Ravi P. Nargund

Journal:

Année:

2009

Fichier:

PDF, 49 KB

2009

3

Pictet-Spengler reaction on solid support

Yang Lihu, Guo Liangqin

Journal:

Tetrahedron Letters

Année:

1996

Langue:

english

Fichier:

PDF, 252 KB

english, 1996

4

Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERα

Kevin D. Dykstra, Liangqin Guo, Elizabeth T. Birzin, Wanda Chan, Yi Tien Yang, Edward C. Hayes, Carolyn A. DaSilva, Lee-Yuh Pai, Ralph T. Mosley, Bryan Kraker, Paula M.D. Fitzgerald, Frank DiNinno, Su

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 841 KB

english, 2007

5

Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist

Zhixiong Ye, Liangqin Guo, Khaled J. Barakat, Patrick G. Pollard, Brenda L. Palucki, Iyassu K. Sebhat, Raman K. Bakshi, Rui Tang, Rubana N. Kalyani, Aurawan Vongs, Airu S. Chen, Howard Y. Chen, Charle

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2005

Langue:

english

Fichier:

PDF, 273 KB

english, 2005

6

α-Aminothiazole-γ-aminobutanoic amides as potent, small molecule CCR2 receptor antagonists

Changyou Zhou, Liangqin Guo, William H. Parsons, Sander G. Mills, Malcolm MacCoss, Pasquale P. Vicario, Hans Zweerink, Margaret A. Cascieri, Martin S. Springer, Lihu Yang

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 163 KB

english, 2007

7

Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators

Liangqin Guo, Zhixiong Ye, Feroze Ujjainwalla, Heather L. Sings, Iyassu K. Sebhat, John Huber, David H. Weinberg, Rui Tang, Tanya MacNeil, Constantin Tamvakopoulos, Qianping Peng, Euan MacIntyre, Lex

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 163 KB

english, 2008

8

Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist

Shuwen He, Zhixiong Ye, Peter H. Dobbelaar, Iyassu K. Sebhat, Liangqin Guo, Jian Liu, Tianying Jian, Yingjie Lai, Christopher L. Franklin, Raman K. Bakshi, James P. Dellureficio, Qingmei Hong, Nancy N

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 454 KB

english, 2010

9

Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands

Qingmei Hong, Raman K. Bakshi, James Dellureficio, Shuwen He, Zhixiong Ye, Peter H. Dobbelaar, Iyassu K. Sebhat, Liangqin Guo, Jian Liu, Tianying Jian, Rui Tang, Rubana N. Kalyani, Tanya MacNeil, Aura

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 293 KB

english, 2010

10

Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4′-piperidine] based melanocortin subtype-4 receptor agonists

Liangqin Guo, Zhixiong Ye, Jian Liu, Shuwen He, Raman K. Bakshi, Iyassu K. Sebhat, Peter H. Dobbelaar, Qingmei Hong, Tianying Jian, James P. Dellureficio, Nancy N. Tsou, Richard G. Ball, David H. Wein

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2010

11

Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity

Shuwen He, Zhixiong Ye, Peter H. Dobbelaar, Iyassu K. Sebhat, Liangqin Guo, Jian Liu, Tianying Jian, Yingjie Lai, Christopher L. Franklin, Raman K. Bakshi, James P. Dellureficio, Qingmei Hong, David H

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2010

12

Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity

Shuwen He, Zhixiong Ye, Peter H. Dobbelaar, Raman K. Bakshi, Qingmei Hong, James P. Dellureficio, Iyassu K. Sebhat, Liangqin Guo, Jian Liu, Tianying Jian, Yingjie Lai, Christopher L. Franklin, Mikhail

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2010

13

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

Qingmei Hong, Raman K. Bakshi, Brenda L. Palucki, Min K. Park, Zhixiong Ye, Shuwen He, Patrick G. Pollard, Iyassu K. Sebhat, Jian Liu, Liangqin Guo, Doreen E. Cashen, William J. Martin, David H. Weinb

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 551 KB

english, 2011

14

Preparation of 3,4-fused-spiro[furan-5(5H),4′-piperidin]-2-one

Jian Liu, Tianying Jian, Liangqin Guo, Tzvetomira Atanasova, Ravi P. Nargund

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2009

15

Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists

Changyou Zhou, Liangqin Guo, Greg Morriello, Alex Pasternak, Yanping Pan, Susan P Rohrer, Elizebeth T Birzin, Su-Er Wu Huskey, Tom Jacks, Klaus D Schleim, Kang Cheng, James M Schaeffer, Arthur A Patch

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 172 KB

english, 2001

16

Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists

Lihu Yang, Changyou Zhou, Liangqin Guo, Gregori Morriello, Gabor Butora, Alexander Pasternak, William H. Parsons, Sander G. Mills, Malcolm MacCoss, Pasquale P. Vicario, Hans Zweerink, Julia M. Ayala,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 150 KB

english, 2006

17

The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes

He, Shuwen, Ye, Zhixiong, Truong, Quang, Shah, Shrenik, Du, Wu, Guo, Liangqin, Dobbelaar, Peter H., Lai, Zhong, Liu, Jian, Jian, Tianying, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio, Ja

Journal:

ACS Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2012

18

Spiro[1 H -indene-1,4‘-piperidine] Derivatives As Potent and Selective Non-Peptide Human Somatostatin Receptor Subtype 2 (sst 2 ) Agonists

Yang, Lihu, Guo, Liangqin, Pasternak, Alexander, Mosley, Ralph, Rohrer, Susan, Birzin, Elizabeth, Foor, Forrest, Cheng, Kang, Schaeffer, James, Patchett, Arthur A.

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 137 KB

english, 1998

19

Synthesis and Biological Activities of Potent Peptidomimetics Selective for Somatostatin Receptor Subtype 2

Lihu Yang, Scott C. Berk, Susan P. Rohrer, Ralph T. Mosley, Liangqin Guo, Dennis J. Underwood, Byron H. Arison, Elizabeth T. Birzin, Edward C. Hayes, Sudha W. Mitra, Rupa M. Parmar, Kang Cheng, Tsuei-

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1998

20

Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists

He, Shuwen, Lai, Zhong, Ye, Zhixiong, Dobbelaar, Peter H., Shah, Shrenik K., Truong, Quang, Du, Wu, Guo, Liangqin, Liu, Jian, Jian, Tianying, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio,

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 302 KB

english, 2014

21

Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists

Li, Derun, Wu, Zhicai, Yu, Yang, Ball, Richard G., Guo, Liangqin, Sherer, Edward, He, Shuwen, Hong, Qingmei, Lai, Zhong, Qi, Hongbo, Truong, Quang, Yang, David X., Chicchi, Gary G., Tsao, Kwei-Lan, Tr

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 940 KB

english, 2014

22

Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Shah, Shrenik K., He, Shuwen, Guo, Liangqin, Truong, Quang, Qi, Hongbo, Du, Wu, Lai, Zhong, Liu, Jian, Jian, Tianying, Hong, Qingmei, Dobbelaar, Peter, Ye, Zhixiong, Sherer, Edward, Feng, Zhe, Yu, Yan

Journal:

ACS Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2015

23

Development of a novel class of potent and selective FIXa inhibitors

Zhang, Ting, Andre, Patrick, Bateman, Thomas J., Chen, Yi-Heng, Desai, Kunal, Ellsworth, Kenneth, Geissler, Wayne M., Guo, Liangqin, Hruza, Alan, Jian, Tianying, Meng, Dongfang, Parker, Dann L., Qian,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2015

24

Development of a novel tricyclic class of potent and selective FIXa inhibitors

Meng, Dongfang, Andre, Patrick, Bateman, Thomas J., Berger, Richard, Chen, Yi-Heng, Desai, Kunal, Dewnani, Sunita, Ellsworth, Kenneth, Feng, Daming, Geissler, Wayne M., Guo, Liangqin, Hruza, Alan, Jia

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 4.08 MB

english, 2015

25

SAR Exploration at the C-3 Position of Tetrahydro-β-carboline sstr3 Antagonists

He, Shuwen, Dobbelaar, Peter H., Guo, Liangqin, Ye, Zhixiong, Liu, Jian, Jian, Tianying, Truong, Quang, Shah, Shrenik K., Du, Wu, Qi, Hongbo, Bakshi, Raman K., Hong, Qingmei, Dellureficio, James D., S

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 683 KB

english, 2016

26

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

Guo, Liangqin, Parker, Dann L., Zang, Yi, Sweis, Ramzi F., Liu, Weiguo, Sherer, Edward C., Buist, Nicole, Terebetski, Jenna, Kelly, Terri, Bugianesi, Randal, Priest, Birgit T., Dingley, Karen H., Li,

Journal:

ACS Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 805 KB

english, 2016

27

Selection and verification of candidate reference genes for gene expression by quantitative RT-PCR in Hibiscus hamabo Sieb.et Zucc.

Ni, Longjie, Wang, Zhiquan, Liu, Liangqin, Guo, Jinbo, Li, Huogen, Gu, Chunsun

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2019

28

Phylogenetic and Transcription Analysis of Hibiscus hamabo Sieb. et Zucc. WRKY Transcription Factors

Wang, Zhiquan, Ni, Longjie, Guo, Jinbo, Liu, Liangqin, Li, Huogen, Yin, Yunlong, Gu, Chunsun

Journal:

DNA and Cell Biology

Année:

2020

Fichier:

PDF, 1.67 MB

2020

29

Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors

Pu, Qinglin, Zhang, Hongjun, Guo, Liangqin, Cheng, Mangeng, Doty, Amy C., Ferguson, Heidi, Fradera, Xavier, Lesburg, Charles A., McGowan, Meredeth A., Miller, J. Richard, Geda, Prasanthi, Song, xuelei

Journal:

ACS Medicinal Chemistry Letters

Année:

2020

Fichier:

PDF, 544 KB

2020